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Structure of 2757082-78-1
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This chiral oxazole features a sterically hindered tert-butyl group and a saturated quinoline core, enabling precise stereochemical control in asymmetric synthesis. The fused tetrahydroquinoline moiety enhances π-stacking potential and solubility in organic media. Designed for integration into complex heterocycles, this scaffold offers robust stability under standard bench conditions and facilitates efficient coupling reactions in medicinal chemistry applications.
(S)-4-(tert-Butyl)-2-(5,6,7,8-tetrahydroquinolin-2-yl)-4,5-dihydrooxazole serves as a versatile chiral building block for the synthesis of bioactive heterocycles. Its oxazole core exhibits robust stability under standard reaction conditions and enables efficient coupling with nucleophiles or transition metal catalysts. The tert-butyl group enhances solubility and facilitates purification, while the tetrahydroquinoline moiety provides a rigid, pharmacophoric scaffold relevant to medicinal chemistry. Functions effectively in Pd-catalyzed cross-coupling and reductive amination workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: