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CS-W001157 4
Total: USD 88.00

(R)-tBu-iQuinox

  • CAS No. 1402851-53-9

  • Cat. No. CS-0087920
  • Molecule weight254.33
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-tBu-iQuinox|CS-0087920

Structure of 1402851-53-9

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General Information

  • CAS No. 1402851-53-9
  • Cat. No. CS-0087920
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₈N₂O
  • Molecular Weight 254.33
  • Synonym(s) 1-[(4R)-4-tert-Butyl-4,5-dihydro-2-oxazolyl]isoquinoline
  • SMILES CC(C)(C)[C@@H]1COC(C2=NC=CC3=CC=CC=C23)=N1

Description

(R)-tBu-iQuinox is a bench-stable, sterically hindered chiral auxiliary designed for asymmetric synthesis. This iQuinox derivative features a bulky tert-butyl group that enhances diastereoselectivity in enantioselective transformations. The rigid quinoxaline scaffold provides predictable stereocontrol, enabling efficient access to complex chiral architectures under mild reaction conditions.

Application

(R)-tBu-iQuinox serves as a chiral auxiliary in asymmetric synthesis, enabling stereoselective construction of quinoxaline-based scaffolds. Its tert-butyl-protected imine functionality provides enhanced bench stability and facilitates straightforward purification. The rigid bicyclic framework supports high diastereoselectivity in key C–C bond-forming reactions, making it a reliable tool for the synthesis of functionalized heterocycles in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.48
  • LogP   3.4263
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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