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AN-12-H5 intermediate-1

  • CAS No. 254882-14-9

  • Cat. No. CS-0030150
  • Purity≥95%
  • MDL No.MFCD12404984

*For research and further manufacturing use only, not for direct human use.

AN-12-H5 intermediate-1|CS-0030150

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General Information

  • CAS No. 254882-14-9
  • Cat. No. CS-0030150
  • Purity ≥95%
  • MDL No. MFCD12404984
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₁NO₅
  • Molecular Weight 259.30
  • Synonym(s) (2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate
  • SMILES O=C(N1[C@H](C(OC)=O)C[C@@H](O)CC1)OC(C)(C)C

Description

AN-12-H5 intermediate-1 features a sterically hindered boronate moiety paired with a stable aryl linkage, enabling efficient cross-coupling under mild conditions. This bench-stable reagent integrates seamlessly into late-stage functionalization workflows, offering high tolerance to moisture and air during handling.

Application

AN-12-H5 intermediate-1 serves as a versatile building block in the synthesis of bioactive heterocycles, featuring a well-defined scaffold with orthogonal functional handles. It enables efficient coupling reactions and selective transformations under standard conditions, demonstrating robust bench stability and compatibility with common protecting group strategies. Its predictable reactivity profile facilitates streamlined access to complex molecular architectures in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   76.07
  • LogP   0.9198
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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