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CS-W001157 4
Total: USD 88.00

4-Methyl-1,3-oxazole-5-carboxylic acid

  • CAS No. 2510-32-9

  • Cat. No. CS-W008834
  • Purity≥95%
  • MDL No.MFCD01571070

*For research and further manufacturing use only, not for direct human use.

4-Methyl-1,3-oxazole-5-carboxylic acid|CS-W008834

Structure of 2510-32-9

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General Information

  • CAS No. 2510-32-9
  • Cat. No. CS-W008834
  • Purity ≥95%
  • MDL No. MFCD01571070
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅NO₃
  • Molecular Weight 127.10
  • Synonym(s) None
  • SMILES O=C(C1=C(C)N=CO1)O

Description

4-Methyl-1,3-oxazole-5-carboxylic acid features a sterically accessible oxazole ring bearing a methyl group at the 4-position and a carboxylic acid at the 5-position. This configuration enables direct incorporation into diverse heterocyclic scaffolds, particularly in medicinal chemistry and peptide conjugation workflows. The compound exhibits bench-stable handling under standard conditions and facilitates efficient derivatization via amide bond formation.

Synthesis

  • Route1
    • null|null
      77287-34-4
    • In-stock
      Ethyl 2-chloroacetoacetate|CS-W018512
      609-15-4
    • ~63%
    • In-stock
      4-Methyl-1,3-oxazole-5-carboxylic acid|CS-W008834
      2510-32-9

    References

    • GLAXO GROUP LIMITED Patent: WO2007/22933 A1, 2007 ; Location in patent: Page/Page column 31-32 ; WO 2007/022933 A1
  • Route2

    References

    • Ray, Sibdas; Ghosh, Sukla Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1999 , vol. 38, # 8 p. 986 - 988
  • Route3

    References

    • Journal of the Chemical Society, , p. 93,95

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.33
  • LogP   0.68122
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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