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(S)-tert-Butyl 4-amino-2-((tert-butoxycarbonyl)amino)butanoate hydrochloride

  • CAS No. 250611-08-6

  • Cat. No. CS-0208935
  • Purity≥95%
  • MDL No.MFCD02259473

*For research and further manufacturing use only, not for direct human use.

(S)-tert-Butyl 4-amino-2-((tert-butoxycarbonyl)amino)butanoate hydrochloride|CS-0208935

Structure of 250611-08-6

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General Information

  • CAS No. 250611-08-6
  • Cat. No. CS-0208935
  • Purity ≥95%
  • MDL No. MFCD02259473
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₇ClN₂O₄
  • Molecular Weight 310.82
  • Synonym(s) Boc-Dab-OtBu·HCl
  • SMILES CC(C)(OC([C@@H](NC(OC(C)(C)C)=O)CCN)=O)C.Cl

Description

(S)-tert-Butyl 4-amino-2-((tert-butoxycarbonyl)amino)butanoate hydrochloride features a chiral backbone with orthogonal protection, enabling selective deprotection during peptide synthesis. The tert-butyl carbamate group offers stability under basic conditions, while the primary amine facilitates efficient coupling reactions. This bench-stable derivative streamlines access to complex amino acid analogs in medicinal chemistry workflows.

Application

(S)-tert-Butyl 4-amino-2-((tert-butoxycarbonyl)amino)butanoate hydrochloride serves as a key chiral building block for the synthesis of peptidomimetics and bioactive heterocycles. The protected amine and amino acid backbone enable straightforward functionalization, while the tert-butyl carbamate group offers stability and orthogonal deprotection. Its bench-stable hydrochloride salt facilitates handling and purification in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   90.65
  • LogP   1.992
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   4

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