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CS-W001157 4
Total: USD 88.00

(R)-4-Amino-2-((tert-butoxycarbonyl)amino)butanoic acid

  • CAS No. 80445-78-9

  • Cat. No. CS-W014793
  • Purity≥95%
  • MDL No.MFCD00798622

*For research and further manufacturing use only, not for direct human use.

(R)-4-Amino-2-((tert-butoxycarbonyl)amino)butanoic acid|CS-W014793

Structure of 80445-78-9

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General Information

  • CAS No. 80445-78-9
  • Cat. No. CS-W014793
  • Purity ≥95%
  • MDL No. MFCD00798622
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈N₂O₄
  • Molecular Weight 218.25
  • Synonym(s) Boc-D-2,4-diaminobutyric acid
  • SMILES O=C(O)[C@H](NC(OC(C)(C)C)=O)CCN

Description

(R)-4-Amino-2-((tert-butoxycarbonyl)amino)butanoic acid is a chiral building block featuring a protected amino group and a free carboxylic acid, enabling direct incorporation into peptide sequences. This configuration supports stereoselective synthesis of bioactive peptides and offers enhanced stability during coupling reactions.

Application

(R)-4-Amino-2-((tert-butoxycarbonyl)amino)butanoic acid serves as a key chiral building block for synthesizing bioactive molecules, particularly in the construction of peptidomimetics and heterocyclic scaffolds. The Boc-protected amine and carboxylic acid functionalities enable orthogonal reactivity in standard coupling and cyclization protocols. Bench-stable and readily purified by crystallization, it facilitates efficient synthesis of complex intermediates under mild conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.65
  • LogP   0.3131
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   4

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