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(S)-tert-Butyl 6-amino-2-((tert-butoxycarbonyl)amino)hexanoate hydrochloride

  • CAS No. 7750-45-0

  • Cat. No. CS-0139598
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-tert-Butyl 6-amino-2-((tert-butoxycarbonyl)amino)hexanoate hydrochloride|CS-0139598

Structure of 7750-45-0

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General Information

  • CAS No. 7750-45-0
  • Cat. No. CS-0139598
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₃₁ClN₂O₄
  • Molecular Weight 338.87
  • Synonym(s) titanium tetrachloride
  • SMILES O=C(OC(C)(C)C)[C@@H](NC(OC(C)(C)C)=O)CCCCN.Cl

Description

(S)-tert-Butyl 6-amino-2-((tert-butoxycarbonyl)amino)hexanoate hydrochloride features a chiral, bench-stable backbone with orthogonal protection for both amine functionalities. This di-functionalized building block integrates seamlessly into peptide synthesis workflows, enabling selective deprotection and chain extension under standard conditions.

Application

(S)-tert-Butyl 6-amino-2-((tert-butoxycarbonyl)amino)hexanoate hydrochloride serves as a key chiral building block for peptide and peptidomimetic synthesis, enabling efficient construction of α,ω-diamino acid scaffolds. The protected amine and carboxylic acid functionalities offer orthogonal reactivity, facilitating sequential coupling reactions with high diastereoselectivity. Bench-stable and readily purified by standard chromatography, it functions effectively in solid-phase and solution-phase workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   90.65
  • LogP   2.7722
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   6

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