1,2-Dimethylpiperazine

Name: 1,2-Dimethylpiperazine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 25057-77-6
Cat. No. CS-W005051
Purity≥98%
MDL No.MFCD08060115

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Description

1,2-Dimethylpiperazine is a sterically hindered, bench-stable piperazine derivative featuring two methyl groups at the 1- and 2-positions. This substitution pattern enhances its nucleophilicity and solubility in polar organic solvents. The compound serves as a key scaffold in medicinal chemistry, integrating into kinase inhibitors and bioactive heterocycles. Its electron-rich nitrogen atoms facilitate efficient coupling reactions under mild conditions.

Application

1,2-Dimethylpiperazine serves as a versatile nitrogen-containing heterocyclic building block in medicinal chemistry and catalysis. Its dual alkylated amine functionality enhances solubility and basicity, enabling efficient coupling reactions and facilitating the synthesis of complex pharmaceutical intermediates. The compound exhibits bench stability and compatibility with common reaction conditions, simplifying purification and scale-up. It functions as a key scaffold for bioactive molecules and catalysts requiring tunable nitrogen environments.

General Information

CAS No. 25057-77-6
Cat. No. CS-W005051
Purity ≥98%
MDL No. MFCD08060115
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₄N₂
Molecular Weight None
Synonym(s) None
SMILES CC1N(C)CCNC1

Computational Chemistry Data

TPSA 15.27
LogP -0.0901
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS02,GHS05
Signal Word : Danger	UN#: 1325
Class : 4.1	Packing Group : Ⅲ
Hazard Statements : H226-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

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1,2-Dimethylpiperazine

CAS No. 25057-77-6

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