Lot numbers can be found on the outside label of a product:
1,2-Dimethylpiperazine
-
CAS No. 25057-77-6
- Cat. No. CS-W005051
- Purity≥98%
- MDL No.MFCD08060115
*For research and further manufacturing use only, not for direct human use.
Structure of 25057-77-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 25057-77-6
- Cat. No. CS-W005051
- Purity ≥98%
- MDL No. MFCD08060115
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₆H₁₄N₂
- Molecular Weight None
- Synonym(s) None
- SMILES CC1N(C)CCNC1
Description
1,2-Dimethylpiperazine is a sterically hindered, bench-stable piperazine derivative featuring two methyl groups at the 1- and 2-positions. This substitution pattern enhances its nucleophilicity and solubility in polar organic solvents. The compound serves as a key scaffold in medicinal chemistry, integrating into kinase inhibitors and bioactive heterocycles. Its electron-rich nitrogen atoms facilitate efficient coupling reactions under mild conditions.
Application
1,2-Dimethylpiperazine serves as a versatile nitrogen-containing heterocyclic building block in medicinal chemistry and catalysis. Its dual alkylated amine functionality enhances solubility and basicity, enabling efficient coupling reactions and facilitating the synthesis of complex pharmaceutical intermediates. The compound exhibits bench stability and compatibility with common reaction conditions, simplifying purification and scale-up. It functions as a key scaffold for bioactive molecules and catalysts requiring tunable nitrogen environments.
Synthesis
-
Route1
-
741287-32-1 - ~%
-
In-stock
25057-77-6
References
-
US2010/35883 A1, ; Page/Page column 92 ;
-
-
Route2
-
In-stock
23936-11-0 - ~%
-
In-stock
25057-77-6
References
-
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 752 - 756
-
-
Route3
-
92699-31-5 - ~%
-
In-stock
25057-77-6
References
-
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 752 - 756
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS02,GHS05
|
|
Signal Word : Danger
|
UN#: 1325
|
|
Class : 4.1
|
Packing Group : Ⅲ
|
|
Hazard Statements : H226-H314
|
|
|
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 15.27
- LogP -0.0901
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 1,2-Dimethylpiperazine sigma1,2-Dimethylpiperazine manufacturer1,2-Dimethylpiperazine price1,2-Dimethylpiperazine structure1,2-Dimethylpiperazine SDSbuy 1,2-Dimethylpiperazine1,2-Dimethylpiperazine supplier1,2-Dimethylpiperazine uses1,2-Dimethylpiperazine molecular weightprice of 1,2-Dimethylpiperazine1,2-Dimethylpiperazine chemical name formula of 1,2-Dimethylpiperazine