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3-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)propanoic acid

  • CAS No. 2412056-29-0

  • Cat. No. CS-0906702
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)propanoic acid|CS-0906702

Structure of 2412056-29-0

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General Information

  • CAS No. 2412056-29-0
  • Cat. No. CS-0906702
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₅N₃O₆
  • Molecular Weight 345.31
  • Synonym(s) None
  • SMILES O=C(CCNC1=CC=C2C(N(C3C(NC(CC3)=O)=O)C(C2=C1)=O)=O)O

Description

This propanoic acid derivative features a fused isoindolinone-piperidinone scaffold, integrating a reactive amine handle for conjugation. The electron-deficient isoindolinone core enhances stability under physiological conditions, while the pendant carboxylic acid enables solubility and bioconjugation versatility.

Application

3-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)propanoic acid serves as a versatile building block for constructing complex heterocyclic scaffolds in medicinal chemistry. Its pendant amino group enables facile derivatization, while the isoindolinone core provides structural rigidity and metabolic stability. The molecule exhibits good bench stability and facilitates efficient coupling reactions under standard conditions, supporting its use in peptide-like conjugate synthesis and target-directed library development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   132.88
  • LogP   -0.6592
  • H_Acceptors   9
  • H_Donors   3
  • Rotatable_Bonds   5

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