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CS-W001157 4
Total: USD 88.00

Pomalidomide 4'-alkylC5-acid

  • CAS No. 2225940-49-6

  • Cat. No. CS-0112522
  • Purity≥95%
  • MDL No.MFCD32063492

*For research and further manufacturing use only, not for direct human use.

Pomalidomide 4'-alkylC5-acid|CS-0112522

Structure of 2225940-49-6

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General Information

  • CAS No. 2225940-49-6
  • Cat. No. CS-0112522
  • Purity ≥95%
  • MDL No. MFCD32063492
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₁N₃O₆
  • Molecular Weight 387.39
  • Synonym(s) None
  • SMILES O=C(O)CCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Description

Pomalidomide 4'-alkylC5-acid features a C5-alkylcarboxylic acid side chain at the 4' position, enhancing solubility and metabolic stability. This modification improves pharmacokinetic handling while preserving target engagement. The derivative integrates readily into medicinal chemistry workflows for targeted protein degradation studies.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   132.88
  • LogP   0.704
  • H_Acceptors   9
  • H_Donors   3
  • Rotatable_Bonds   8

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