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CS-W001157 4
Total: USD 88.00

Thalidomide-NH-CH2-COOH

  • CAS No. 927670-97-1

  • Cat. No. CS-0138986
  • Purity≥95%
  • MDL No.MFCD31667076

*For research and further manufacturing use only, not for direct human use.

Thalidomide-NH-CH2-COOH|CS-0138986

Structure of 927670-97-1

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General Information

  • CAS No. 927670-97-1
  • Cat. No. CS-0138986
  • Purity ≥95%
  • MDL No. MFCD31667076
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₃N₃O₆
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(O)CNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Description

The reaction of phenylmercury (II) chloride with acetophenonethiosemicarbazone (Hatsc) in ethanol in 1: 1 mole ratio undergoes symmetrisation forming the products, HgCl2 (Hatse) 2 and Ph2Hg instead of the anticipated compound PhHgCl (Hatse). A new method for the determination of chloride ion is based on the formation of phenylmercury(II) chloride, its extraction into chloroform and reaction with sodium diethyldithiocarbamate to form phenylmercury(II) diethyldithiocarbamate.

Application

Thalidomide-NH-CH₂-COOH serves as a versatile scaffold for targeted molecular diversification, enabling the construction of imide-based heterocycles and peptide conjugates. Its amide and carboxylic acid functionalities facilitate robust coupling reactions, offering enhanced solubility and metabolic stability in medicinal chemistry applications.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H312-H361
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   132.88
  • LogP   -1.1136
  • H_Acceptors   9
  • H_Donors   3
  • Rotatable_Bonds   4

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