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CS-W001157 4
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tert-Butyl 1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate

  • CAS No. 230301-11-8

  • Cat. No. CS-D1539
  • Purity≥95%
  • MDL No.MFCD08059268

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate|CS-D1539

Structure of 230301-11-8

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General Information

  • CAS No. 230301-11-8
  • Cat. No. CS-D1539
  • Purity ≥95%
  • MDL No. MFCD08059268
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇N₃O₂
  • Molecular Weight 223.27
  • Synonym(s) 7-dihydro-1H-pyrazolo[4
  • SMILES O=C(N1CCC(NN=C2)=C2C1)OC(C)(C)C

Description

tert-Butyl 1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate is a bench-stable heterocyclic building block featuring a fused pyrazolopyridine core. This compound integrates readily into medicinal chemistry campaigns due to its compatibility with standard coupling and reduction protocols. The tert-butyl ester moiety enables selective deprotection under mild acidic conditions, facilitating downstream functionalization.

Application

tert-Butyl 1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and synthetic organic applications. The protected pyrazolopyridine core enables straightforward functionalization at the C5 position and supports downstream transformations such as hydrogenation, substitution, and coupling reactions. Its tert-butyl ester group provides excellent bench stability and facilitates purification, while the scaffold exhibits favorable solubility and compatibility with standard reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.22
  • LogP   1.7029
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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