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4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine dihydrochloride

  • CAS No. 157327-44-1

  • Cat. No. CS-0036544
  • Purity≥95%
  • MDL No.MFCD05864362

*For research and further manufacturing use only, not for direct human use.

4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine dihydrochloride|CS-0036544

Structure of 157327-44-1

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General Information

  • CAS No. 157327-44-1
  • Cat. No. CS-0036544
  • Purity ≥95%
  • MDL No. MFCD05864362
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁Cl₂N₃
  • Molecular Weight 196.08
  • Synonym(s) None
  • SMILES C12=C(NN=C2)CCNC1.Cl.Cl

Description

This tetrahydro-pyrazolo[4,3-c]pyridine dihydrochloride offers a rigid, electron-rich heterocyclic core ideal for medicinal chemistry applications. The dihydrochloride salt enhances solubility and stability under standard conditions, facilitating incorporation into synthetic routes requiring polar, bench-stable intermediates.

Application

4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine dihydrochloride serves as a versatile heterocyclic building block for medicinal chemistry and process development. Its saturated pyrazolopyridine core exhibits excellent bench stability and functional group tolerance, enabling straightforward derivatization via standard coupling and alkylation protocols. The dihydrochloride salt form enhances solubility and crystallinity, facilitating purification and handling in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.71
  • LogP   0.899
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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