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CS-W001157 4
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(4-(Piperidin-1-yl)phenyl)boronic acid

  • CAS No. 229009-42-1

  • Cat. No. CS-0044979
  • Purity≥97%
  • MDL No.MFCD03095171

*For research and further manufacturing use only, not for direct human use.

(4-(Piperidin-1-yl)phenyl)boronic acid|CS-0044979

Structure of 229009-42-1

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General Information

  • CAS No. 229009-42-1
  • Cat. No. CS-0044979
  • Purity ≥97%
  • MDL No. MFCD03095171
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆BNO₂
  • Molecular Weight 205.06
  • Synonym(s) 4-(1-PIPERIDINYL)PHENYLBORONIC ACID HCL
  • SMILES OB(C1=CC=C(N2CCCCC2)C=C1)O

Description

This boronate moiety integrates a piperidinyl group at the para position of a phenyl ring, delivering enhanced solubility and stability under standard conditions. The electron-rich aromatic system facilitates efficient Suzuki-Miyaura coupling, enabling robust C–C bond formation in complex molecule synthesis.

Application

(4-(Piperidin-1-yl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The piperidinyl group enhances solubility and modulates electronic properties, while the boronic acid functionality offers excellent stability, ease of handling, and compatibility with diverse functional groups, making it well-suited for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.7
  • LogP   0.3567
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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