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CS-W001157 4
Total: USD 88.00

2-Phenylpiperidine

  • CAS No. 3466-80-6

  • Cat. No. CS-0028391
  • Purity≥97%
  • MDL No.MFCD00270125

*For research and further manufacturing use only, not for direct human use.

2-Phenylpiperidine|CS-0028391

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General Information

  • CAS No. 3466-80-6
  • Cat. No. CS-0028391
  • Purity ≥97%
  • MDL No. MFCD00270125
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅N
  • Molecular Weight 161.24
  • Synonym(s) ART-CHEM-BB B022867
  • SMILES C1(C2=CC=CC=C2)NCCCC1

Description

2-Phenylpiperidine is a versatile heterocyclic scaffold featuring a phenyl ring fused to a piperidine core, offering enhanced lipophilicity and metabolic stability. This structural motif serves as a key pharmacophore in CNS-targeted therapeutics, enabling efficient membrane penetration and target engagement.

Application

2-Phenylpiperidine serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive molecules through well-established functionalization at the piperidine nitrogen and aromatic ring. Its bench-stable nature and compatibility with common coupling and reduction protocols facilitate efficient synthesis of CNS-targeted compounds. Functions as a key building block for opioid receptor ligands and other pharmacologically relevant heterocycles.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   2.5012
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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