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CS-W001157 4
Total: USD 88.00

Thalidomide-Piperazine 5-fluoride hydrochloride

  • CAS No. 2222114-23-8

  • Cat. No. CS-0214367
  • Molecule weight396.80
  • Purity≥98%
  • MDL No.MFCD32203462

*For research and further manufacturing use only, not for direct human use.

Thalidomide-Piperazine 5-fluoride hydrochloride|CS-0214367

Structure of 2222114-23-8

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General Information

  • CAS No. 2222114-23-8
  • Cat. No. CS-0214367
  • Purity ≥98%
  • MDL No. MFCD32203462
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₈ClFN₄O₄
  • Molecular Weight 396.80
  • Synonym(s) None
  • SMILES O=C1NC(C(CC1)N2C(C3=CC(F)=C(N4CCNCC4)C=C3C2=O)=O)=O.Cl

Description

Thalidomide-Piperazine 5-fluoride (hydrochloride) integrates a piperazine-modified thalidomide scaffold with a 5-fluoride substituent, enhancing solubility and metabolic stability. This derivative leverages the immunomodulatory framework of thalidomide while introducing targeted electronic effects through the fluorinated aryl moiety, enabling precise engagement with biological targets in oncology and inflammatory pathways.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H361
Precautionary Statements : P264-P270-P280-P330-P405-P501

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Computational Chemistry Data

  • TPSA   98.82
  • LogP   -0.2643
  • H_Acceptors   8
  • H_Donors   2
  • Rotatable_Bonds   2

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