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CS-W001157 4
Total: USD 88.00

(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-prop-2-enoxycarbonylphenyl)propanoic acid

  • CAS No. 2196198-73-7

  • Cat. No. CS-0771387
  • Molecule weight471.50
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-prop-2-enoxycarbonylphenyl)propanoic acid|CS-0771387

Structure of 2196198-73-7

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General Information

  • CAS No. 2196198-73-7
  • Cat. No. CS-0771387
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₈H₂₅NO₆
  • Molecular Weight 471.50
  • Synonym(s) None
  • SMILES OC(=O)[C@H](CC1=CC=C(C=C1)C(=O)OCC=C)NC(=O)OCC1C2=C(C=CC=C2)C2=C1C=CC=C2

Description

This fluoren-9-ylmethoxycarbonyl-protected amino acid derivative features a prop-2-enoxycarbonyl-substituted phenyl group, enabling efficient coupling in peptide synthesis. The C-terminal ester facilitates rapid activation and incorporation into oligopeptide chains under standard conditions.

Application

(2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-prop-2-enoxycarbonylphenyl)propanoic acid serves as a robust chiral building block for peptide synthesis, enabling efficient formation of sterically constrained C-terminal amino acid derivatives. The fluorenylmethoxycarbonyl (Fmoc) group provides excellent stability and ease of removal under mild basic conditions, while the prop-2-enoxycarbonyl aryl moiety offers compatibility with standard coupling protocols. Its defined stereochemistry and functional group tolerance facilitate reliable incorporation into complex peptide scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   4.5638
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   9

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