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CS-W001157 4
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(4S,4'S)-2,2'-Cyclohexylidenebis[4,5-dihydro-4-phenyloxazole]

  • CAS No. 2185014-88-2

  • Cat. No. CS-0097887
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4S,4'S)-2,2'-Cyclohexylidenebis[4,5-dihydro-4-phenyloxazole]|CS-0097887

Structure of 2185014-88-2

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General Information

  • CAS No. 2185014-88-2
  • Cat. No. CS-0097887
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₆N₂O₂
  • Molecular Weight 374.48
  • Synonym(s) None
  • SMILES C1(C2(CCCCC2)C3=N[C@@H](C4=CC=CC=C4)CO3)=N[C@@H](C5=CC=CC=C5)CO1

Description

This chiral bis-oxazole scaffold features a rigid cyclohexylidene bridge that enforces defined spatial orientation, enabling precise molecular recognition. The dihydrooxazole rings provide stability and polarity, while the phenyl substituents enhance π-interactions. Ideal for asymmetric synthesis and catalyst design, this compound integrates seamlessly into complex architectures requiring controlled stereochemistry and robust handling under standard conditions.

Application

(4S,4'S)-2,2'-Cyclohexylidenebis[4,5-dihydro-4-phenyloxazole] serves as a chiral bis-oxazole scaffold with defined stereochemistry at the 4 and 4' positions. It functions as a versatile building block in asymmetric synthesis, enabling controlled construction of complex heterocyclic architectures. The cyclohexylidene linker provides rigidity and enhances structural integrity, while the dihydrooxazole moieties offer functional group tolerance for downstream transformations. Its bench-stable nature and predictable reactivity facilitate integration into standard synthetic workflows for medicinal chemistry and catalytic system development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   5.2769
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

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