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(4R,​4'R)​-2,​2'-​Cyclopentylidenebis[​4,​5-​dihydro-​4-​phenyloxazole]

  • CAS No. 1246401-49-9

  • Cat. No. CS-0086735
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4R,​4'R)​-2,​2'-​Cyclopentylidenebis[​4,​5-​dihydro-​4-​phenyloxazole]|CS-0086735

Structure of 1246401-49-9

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General Information

  • CAS No. 1246401-49-9
  • Cat. No. CS-0086735
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₄N₂O₂
  • Molecular Weight 360.45
  • Synonym(s) (4R,4'R)-2,2'-(Cyclopentane-1,1-diyl)-bis(4-phenyl-4,5-dihydrooxazole)
  • SMILES C1(C2(C3=N[C@H](C4=CC=CC=C4)CO3)CCCC2)=N[C@H](C5=CC=CC=C5)CO1

Description

This chiral bis-oxazole features a rigid cyclopentylidene bridge linking two 4-phenyloxazole rings, offering enhanced stereochemical stability and defined spatial orientation. Designed for asymmetric synthesis applications, it integrates readily into catalytic systems requiring precise steric and electronic control.

Application

(4R,4'R)-2,2'-Cyclopentylidenebis[4,5-dihydro-4-phenyloxazole] serves as a chiral bis-oxazole scaffold with defined stereochemistry, enabling stereoselective synthesis in asymmetric catalysis and medicinal chemistry. Its rigid, planar structure enhances conformational control in target-directed synthesis, while the oxazole rings offer good bench stability and orthogonal reactivity for downstream functionalization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   4.8868
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   4

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