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(6-Methoxypyridin-2-yl)methanamine dihydrochloride

  • CAS No. 2172852-89-8

  • Cat. No. CS-0162259
  • Molecule weight211.09
  • Purity≥97%
  • MDL No.MFCD31619130

*For research and further manufacturing use only, not for direct human use.

(6-Methoxypyridin-2-yl)methanamine dihydrochloride|CS-0162259

Structure of 2172852-89-8

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General Information

  • CAS No. 2172852-89-8
  • Cat. No. CS-0162259
  • Purity ≥97%
  • MDL No. MFCD31619130
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂Cl₂N₂O
  • Molecular Weight 211.09
  • Synonym(s) 1-(6-Methoxy-2-pyridinyl)methanamine dihydrochloride
  • SMILES NCC1=NC(OC)=CC=C1.[H]Cl.[H]Cl

Description

This bench-stable dihydrochloride salt features a 6-methoxypyridin-2-ylmethanamine core, offering enhanced solubility and handling convenience. The electron-rich pyridine ring enables efficient coupling reactions, while the amine functionality facilitates straightforward derivatization in medicinal chemistry workflows.

Application

(6-Methoxypyridin-2-yl)methanamine dihydrochloride serves as a versatile building block for medicinal chemistry and catalytic synthesis, enabling efficient access to pyridine-based pharmacophores. Its amine functionality facilitates straightforward derivatization via alkylation, acylation, and coupling reactions, while the methoxy group provides orthogonal reactivity and enhanced solubility. The dihydrochloride salt form ensures excellent bench stability, ease of handling, and compatibility with standard purification protocols in multi-step synthesis.

Safety Information

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Computational Chemistry Data

  • TPSA   48.14
  • LogP   1.3925
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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