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CS-W001157 4
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3-(Aminomethyl)oxetan-3-ol

  • CAS No. 1305208-47-2

  • Cat. No. CS-0051726
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Aminomethyl)oxetan-3-ol|CS-0051726

Structure of 1305208-47-2

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General Information

  • CAS No. 1305208-47-2
  • Cat. No. CS-0051726
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉NO₂
  • Molecular Weight 103.12
  • Synonym(s) 3-hydroxy-3-aminomethyloxetane
  • SMILES NCC1(O)COC1

Description

3-(Aminomethyl)oxetan-3-ol delivers a reactive oxetane ring paired with a primary amine handle, enabling efficient conjugation in bioconjugation and medicinal chemistry. This bench-stable, moisture-tolerant scaffold integrates seamlessly into peptide and small-molecule architectures, offering enhanced solubility and metabolic stability in drug discovery applications.

Application

3-(Aminomethyl)oxetan-3-ol serves as a versatile building block in medicinal chemistry, enabling the introduction of a polar, metabolically stable oxetane ring with a primary amine handle. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of bioactive molecules, particularly in targeted kinase inhibitors and CNS-penetrant drug candidates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.48
  • LogP   -1.2936
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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