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Structure of 2135600-87-0
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This bench-stable, moisture-tolerant amine features a fluorinated benzofuran scaffold that enhances metabolic stability and modulates electronic properties. The para-fluoro substitution improves target binding affinity while the hydrochloride salt ensures high solubility and ease of handling in synthetic workflows.
(5-Fluoro-2,3-dihydrobenzofuran-4-yl)methanamine hydrochloride serves as a versatile building block for medicinal chemistry, enabling efficient access to bioactive heterocycles. The scaffold features a fluorinated dihydrobenzofuran core with a primary amine handle, offering excellent functional group tolerance and stability under standard synthetic conditions. It facilitates rapid diversification via amide coupling, reductive amination, and electrophilic substitution, making it well-suited for lead optimization campaigns in CNS and oncology drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: