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CS-W001157 4
Total: USD 88.00

2-Amino-5-fluoropyridine

  • CAS No. 21717-96-4

  • Cat. No. CS-B0957
  • Purity≥98%
  • MDL No.MFCD01861120

*For research and further manufacturing use only, not for direct human use.

2-Amino-5-fluoropyridine|CS-B0957

Structure of 21717-96-4

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General Information

  • CAS No. 21717-96-4
  • Cat. No. CS-B0957
  • Purity ≥98%
  • MDL No. MFCD01861120
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅FN₂
  • Molecular Weight 112.11
  • Synonym(s) None
  • SMILES NC1=NC=C(F)C=C1

Description

2-Amino-5-fluoropyridine features a strategically positioned fluorine atom and amino group on the pyridine ring, enabling efficient incorporation into bioactive molecules. This electron-deficient heterocycle serves as a key scaffold in medicinal chemistry, offering enhanced metabolic stability and tunable basicity for targeted drug design.

Application

2-Amino-5-fluoropyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to fluorinated heterocyclic scaffolds. Its dual functionalization—amine and fluorine—supports diverse transformations including Suzuki-Miyaura coupling, nucleophilic substitution, and transition-metal-catalyzed cross-couplings. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic campaigns and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   0.8029
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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