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Structure of 868636-72-0
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5-Fluoro-N-methylpyridin-2-amine features a fluorinated pyridine core with a methylamino substituent at the 2-position, delivering enhanced electron density and improved metabolic stability. This bench-stable heterocycle integrates readily into pharmaceutical scaffolds, serving as a key building block for kinase inhibitors and CNS-targeted therapeutics.
5-Fluoro-N-methylpyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard cross-coupling and nucleophilic substitution reactions. Its fluorinated pyridine core offers enhanced metabolic stability and modulated basicity, while the N-methyl group improves lipophilicity and membrane permeability. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: