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Structure of 21319-53-9
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1-Benzylpiperidine-2-carboxylic acid features a rigid, electron-rich piperidine core functionalized with a benzyl group and a carboxylic acid at the 2-position, enabling direct incorporation into bioactive scaffolds. This structure supports hydrogen bonding and dipole interactions, enhancing target affinity in medicinal chemistry applications.
1-Benzylpiperidine-2-carboxylic acid serves as a versatile scaffold for medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its benzylic piperidine core offers enhanced metabolic stability and favorable physicochemical properties, while the carboxylic acid group facilitates direct derivatization or incorporation into peptide-like structures. The compound exhibits good bench stability and is amenable to purification via standard chromatographic techniques, supporting its use in iterative synthesis campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: