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1,3-Bisbenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid

  • CAS No. 59564-78-2

  • Cat. No. CS-0156311
  • Purity≥97%
  • MDL No.MFCD06798134

*For research and further manufacturing use only, not for direct human use.

1,3-Bisbenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid|CS-0156311

Structure of 59564-78-2

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General Information

  • CAS No. 59564-78-2
  • Cat. No. CS-0156311
  • Purity ≥97%
  • MDL No. MFCD06798134
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₈N₂O₅
  • Molecular Weight 354.36
  • Synonym(s) 1,3-Dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid
  • SMILES C1=CC=C(C=C1)CN2C(C(C(=O)O)N(CC3=CC=CC=C3)C2=O)C(=O)O

Description

1,3-Bisbenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid features a rigid imidazolidine core with two benzyl substituents and flanking carboxylic acid groups, enabling efficient integration into peptidomimetic scaffolds. The molecule exhibits enhanced solubility and stability under standard bench conditions, facilitating use in synthetic medicinal chemistry workflows.

Application

1,3-Bisbenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to imidazolidine-based scaffolds. Its orthogonal functional groups facilitate selective derivatization, while the dicarboxylic acid moiety enhances solubility and simplifies purification. Bench-stable and compatible with standard coupling protocols, it functions effectively in medicinal chemistry campaigns requiring rigid, polar frameworks.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   98.15
  • LogP   2.0308
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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