Boc-Pip-OH

Name: Boc-Pip-OH
Brand: ChemScene
Availability: InStock
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CAS No. 26250-84-0
Cat. No. CS-W007743
Purity≥97%
MDL No.MFCD00151904

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 26250-84-0

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General Information

CAS No. 26250-84-0
Cat. No. CS-W007743
Purity ≥97%
MDL No. MFCD00151904
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₉NO₄
Molecular Weight 229.28
Synonym(s) Boc-L-pipecolic acid
SMILES [C@@H]1(N(C(OC(C)(C)C)=O)CCCC1)C(=O)O

Description

Boc-Pip-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a tert-butoxycarbonyl-protected primary amine and a terminal hydroxyl group. This combination enables straightforward coupling reactions in peptide synthesis workflows, where the Boc group facilitates selective deprotection and the hydroxyl moiety supports derivatization or conjugation.

Synthesis

Route1
- 259133-67-0
- ~87%
- In-stock
  
  26250-84-0
References
- Wilkinson; Stehle; Beak Organic letters, 2000 , vol. 2, # 2 p. 155 - 158
Route2
- 7681-38-1
- 13406-98-9
- In-stock
  
  24424-99-5
- ~72%
- In-stock
  
  26250-84-0
References
- Agouron Pharmaceuticals, Inc. Patent: US5484926 A1, 1996 ;
Route3
- In-stock
  
  24424-99-5
- In-stock
  
  3105-95-1
- ~10%
- In-stock
  
  26250-84-0
References
- Thai, Dung L.; Sapko, Michael T.; Reiter, Clara T.; Bierer, Donald E.; Perel, James M. Journal of Medicinal Chemistry, 1998 , vol. 41, # 4 p. 591 - 601

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 66.84
LogP 1.8606
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Boc

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Unnatural Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Boc-Pip-OH

CAS No. 26250-84-0

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