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CS-W001157 4
Total: USD 88.00

(S)-SEGPHOS

  • CAS No. 210169-54-3

  • Cat. No. CS-W020802
  • Purity≥98%
  • MDL No.MFCD09753005

*For research and further manufacturing use only, not for direct human use.

(S)-SEGPHOS|CS-W020802

Structure of 210169-54-3

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General Information

  • CAS No. 210169-54-3
  • Cat. No. CS-W020802
  • Purity ≥98%
  • MDL No. MFCD09753005
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₈H₂₈O₄P₂
  • Molecular Weight 610.57
  • Synonym(s) (S)-(-)-SEGPHOS®
  • SMILES C1(OCO2)=C2[C@@]([C@@]3=C(OCO4)C4=CC=C3P(C5=CC=CC=C5)C6=CC=CC=C6)=C(P(C7=CC=CC=C7)C8=CC=CC=C8)C=C1

Application

(S)-SEGPHOS is a chiral bisphosphine ligand that enables highly enantioselective transition metal-catalyzed reactions, particularly in palladium- and nickel-mediated cross-couplings. Its rigid biaryl backbone and sterically defined phosphorus centers provide excellent control over stereochemistry, facilitating efficient asymmetric synthesis of complex intermediates. The ligand exhibits robust bench stability, ease of handling, and compatibility with diverse functional groups, making it a reliable choice for industrial and academic applications requiring high enantiomeric purity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   36.92
  • LogP   6.3274
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   7

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