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CS-W001157 4
Total: USD 88.00

(S)-DTBM-SEGPHOS

  • CAS No. 210169-40-7

  • Cat. No. CS-W020801
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-DTBM-SEGPHOS|CS-W020801

Structure of 210169-40-7

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General Information

  • CAS No. 210169-40-7
  • Cat. No. CS-W020801
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇₄H₁₀₀O₈P₂
  • Molecular Weight 1179.53
  • Synonym(s) (S)-(+)-DTBM-SEGPHOS®
  • SMILES CC(C)(C)C1=CC([P]C2=[C@]([C@]3=C(OCO4)C4=CC=C3[P]C5=CC(C(C)(C)C)=C(OC)C(C(C)(C)C)=C5)C6=C(OCO6)C=C2)=CC(C(C)(C)C)=C1OC

Application

(S)-DTBM-SEGPHOS is a chiral bisphosphine ligand that enables highly enantioselective transition-metal-catalyzed cross-coupling reactions. It functions effectively in palladium- and nickel-catalyzed processes, offering excellent stereocontrol in the synthesis of chiral biaryl and allylic systems. Its steric and electronic properties enhance reactivity and stability under standard reaction conditions, facilitating efficient purification and scalable applications in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.38
  • LogP   9.2768
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   7

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