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CS-W001157 4
Total: USD 88.00

(R)-SEGPHOS

  • CAS No. 244261-66-3

  • Cat. No. CS-0035252
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-SEGPHOS|CS-0035252

Structure of 244261-66-3

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General Information

  • CAS No. 244261-66-3
  • Cat. No. CS-0035252
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₈H₂₈O₄P₂
  • Molecular Weight 610.57
  • Synonym(s) (R)-(+)-SEGPHOS; Segphos
  • SMILES C1(OCO2)=C2C(C3=C(OCO4)C4=CC=C3P(C5=CC=CC=C5)C6=CC=CC=C6)=C(P(C7=CC=CC=C7)C8=CC=CC=C8)C=C1

Application

(R)-SEGPHOS is a chiral bisphosphine ligand that enables highly enantioselective palladium-catalyzed cross-coupling reactions. It functions effectively in Suzuki-Miyaura, Negishi, and Stille couplings, offering excellent stereocontrol and robust performance under standard reaction conditions. Its bench-stable nature and compatibility with diverse functional groups make it a practical choice for asymmetric synthesis in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   36.92
  • LogP   6.3274
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   7

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