Lenalidomide-Br

Name: Lenalidomide-Br
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2093387-36-9
Cat. No. CS-0091191
Purity≥98%
MDL No.MFCD32063479

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 2093387-36-9

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General Information

CAS No. 2093387-36-9
Cat. No. CS-0091191
Purity ≥98%
MDL No. MFCD32063479
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₁BrN₂O₃
Molecular Weight 323.14
Synonym(s) None
SMILES O=C(C(N(CC1=C2C=CC=C1Br)C2=O)CC3)NC3=O

Description

Lenalidomide-Br features a brominated derivative of lenalidomide, incorporating a reactive bromine atom at the C5 position of the phthalimide ring. This modification enables site-specific conjugation in bioorthogonal labeling strategies and facilitates downstream derivatization for targeted drug delivery systems. The compound maintains the core pharmacophore essential for immunomodulatory activity while enhancing synthetic versatility.

Application

Lenalidomide-Br serves as a versatile bromo-functionalized derivative of lenalidomide, enabling site-specific conjugation and downstream derivatization in medicinal chemistry workflows. Its reactive bromine atom facilitates palladium-catalyzed cross-coupling reactions, supporting the construction of diverse analogs for target validation and structure-activity relationship studies. The compound exhibits good bench stability and compatibility with common reaction conditions, making it a practical tool for scaffold diversification in oncology and immunomodulatory research.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

TPSA 66.48
LogP 0.6642
H_Acceptors 5
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Life Science PROTAC Ligands for E3 Ligase

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Other aromatic heterocycles compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Biochemistry Biochemicals and Reagents Bioactive Compounds (Other)

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

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Lenalidomide-Br

CAS No. 2093387-36-9

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