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CS-W001157 4
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Tetrahydrofuran-3-amine hydrochloride

  • CAS No. 204512-94-7

  • Cat. No. CS-D1564
  • Purity≥97%
  • MDL No.MFCD06738925

*For research and further manufacturing use only, not for direct human use.

Tetrahydrofuran-3-amine hydrochloride|CS-D1564

Structure of 204512-94-7

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General Information

  • CAS No. 204512-94-7
  • Cat. No. CS-D1564
  • Purity ≥97%
  • MDL No. MFCD06738925
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO
  • Molecular Weight 123.58
  • Synonym(s) 3-Aminotetrahydrofuran hydrochloride; Tetrahydrofuran-3-amine hydrochloride; Tetrahydrofuran-3-ylamine hydrochloride; 3-Furanamine,tetrahydro-, hydrochloride (9CI)
  • SMILES NC1COCC1.[H]Cl

Description

Tetrahydrofuran-3-amine hydrochloride features a tertiary amine embedded within a saturated five-membered ring, delivering high solubility in polar solvents and stability under standard conditions. This bench-stable derivative serves as a key scaffold for bioactive molecule synthesis, particularly in medicinal chemistry applications requiring nitrogen incorporation.

Application

Tetrahydrofuran-3-amine hydrochloride serves as a versatile nitrogen-containing building block in medicinal chemistry and synthetic organic applications. The amine functionality enables straightforward derivatization for peptide-like scaffolds and heterocycle synthesis. Its hydrochloride salt form enhances bench stability, solubility, and ease of handling, facilitating purification and compatibility with standard reaction conditions. Functions effectively in nucleophilic substitution and coupling reactions, particularly in the construction of bioactive heterocyclic frameworks.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   0.1558
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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