(R)-3-Aminotetrahydrofuran hydrochloride

Name: (R)-3-Aminotetrahydrofuran hydrochloride
Brand: ChemScene
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CAS No. 1072015-52-1
Cat. No. CS-W019413
Purity≥97%
MDL No.MFCD08461720

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(R)-3-Aminotetrahydrofuran hydrochloride|CS-W019413

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General Information

CAS No. 1072015-52-1
Cat. No. CS-W019413
Purity ≥97%
MDL No. MFCD08461720
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₁₀ClNO
Molecular Weight 123.58
Synonym(s) [(3R)-tetrahydrofuran-3-yl]ammonium chloride
SMILES N[C@@H]1CCOC1.Cl

Description

(R)-3-Aminotetrahydrofuran hydrochloride delivers a chiral, bench-stable amine handle within a saturated heterocyclic framework. This configuration enables precise stereochemical control in asymmetric synthesis, serving as a key scaffold for bioactive molecule construction. The hydrochloride salt enhances solubility and handling in aqueous or polar organic media.

Application

(R)-3-Aminotetrahydrofuran hydrochloride serves as a chiral building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its well-defined stereochemistry enables stereoselective transformations, while the amine functionality facilitates facile derivatization via amidation, alkylation, or reductive amination. The hydrochloride salt enhances bench stability and solubility, simplifying purification and handling in standard synthetic workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 35.25
LogP 0.1558
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Key Words

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(R)-3-Aminotetrahydrofuran hydrochloride

CAS No. 1072015-52-1

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