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CS-W001157 4
Total: USD 88.00

5-Bromo-2-nitrobenzaldehyde

  • CAS No. 20357-20-4

  • Cat. No. CS-W004818
  • Purity≥95%
  • MDL No.MFCD00456508

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-nitrobenzaldehyde|CS-W004818

Structure of 20357-20-4

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General Information

  • CAS No. 20357-20-4
  • Cat. No. CS-W004818
  • Purity ≥95%
  • MDL No. MFCD00456508
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrNO₃
  • Molecular Weight 230.02
  • Synonym(s) CU48750000
  • SMILES O=CC1=CC(Br)=CC=C1[N+]([O-])=O

Description

5-Bromo-2-nitrobenzaldehyde features a bromine atom at the 5-position and a nitro group at the 2-position, creating a strongly electron-deficient aromatic ring. This configuration enhances reactivity in cross-coupling and nucleophilic substitution processes. The aldehyde functionality enables direct incorporation into complex molecular architectures under mild conditions. Bench-stable and moisture-tolerant, it serves as a valuable building block for pharmaceutical intermediates and functional materials.

Synthesis

  • Route1
    • null|null
      105205-48-9
    • ~70%
    • In-stock
      5-Bromo-2-nitrobenzaldehyde|CS-W004818
      20357-20-4

    References

    • WO2006/76529 A1, ; Page/Page column 92; 93 ;
  • Route2

    References

    • Chemistry - A European Journal, , vol. 19, # 7 p. 2442 - 2449
  • Route3

    References

    • Synthetic Communications, , vol. 44, # 7 p. 954 - 958

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   60.21
  • LogP   2.1698
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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