Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromo-6-nitrobenzaldehyde

  • CAS No. 20357-21-5

  • Cat. No. CS-0012639
  • Purity≥98%
  • MDL No.MFCD09040530

*For research and further manufacturing use only, not for direct human use.

2-Bromo-6-nitrobenzaldehyde|CS-0012639

Structure of 20357-21-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 20357-21-5
  • Cat. No. CS-0012639
  • Purity ≥98%
  • MDL No. MFCD09040530
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrNO₃
  • Molecular Weight 230.02
  • Synonym(s) 2-Brom-6-nitro-benzaldehyd
  • SMILES O=CC1=C([N+]([O-])=O)C=CC=C1Br

Description

2-Bromo-6-nitrobenzaldehyde features a bromine atom and a nitro group positioned ortho to the aldehyde functionality, creating a highly electron-deficient aromatic scaffold. This combination enables efficient coupling reactions in cross-coupling and multistep synthesis, particularly in pharmaceutical intermediates and functional materials. The aldehyde remains reactive under standard conditions, facilitating further derivatization.

Application

2-Bromo-6-nitrobenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the aldehyde and nitro positions. Its ortho-bromine facilitates palladium-catalyzed cross-coupling reactions, while the electron-withdrawing nitro group enhances electrophilicity for nucleophilic substitution or condensation processes. The compound exhibits good bench stability and is compatible with standard purification techniques, making it a reliable reagent for constructing complex heterocyclic scaffolds and advanced intermediates in medicinal chemistry and materials science.

Synthesis

  • Route1

    References

    • Angewandte Chemie - International Edition, , vol. 45, # 40 p. 6737 - 6741
  • Route2
    • In-stock
      5-Bromo-3-methylquinoline|CS-W007179
      397322-46-2
    • null|null
      34241-39-9
    • ~25%
    • In-stock
      2-Bromo-6-nitrobenzaldehyde|CS-0012639
      20357-21-5

    References

    • EP1479384 A1, ;
  • Route3
    • In-stock
      5-Bromo-3-methylquinoline|CS-W007179
      397322-46-2
    • null|null
      397321-54-9
    • null|null
      34241-39-9
    • ~26%
    • In-stock
      2-Bromo-6-nitrobenzaldehyde|CS-0012639
      20357-21-5

    References

    • US2003/181496 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.21
  • LogP   2.1698
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Bromo-6-nitrobenzaldehyde sigma2-Bromo-6-nitrobenzaldehyde manufacturer2-Bromo-6-nitrobenzaldehyde price2-Bromo-6-nitrobenzaldehyde structure2-Bromo-6-nitrobenzaldehyde SDSbuy 2-Bromo-6-nitrobenzaldehyde2-Bromo-6-nitrobenzaldehyde supplier2-Bromo-6-nitrobenzaldehyde uses2-Bromo-6-nitrobenzaldehyde molecular weightprice of 2-Bromo-6-nitrobenzaldehyde2-Bromo-6-nitrobenzaldehyde chemical name formula of 2-Bromo-6-nitrobenzaldehyde
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label