Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Chloro-2-nitrobenzaldehyde

  • CAS No. 6628-86-0

  • Cat. No. CS-W007862
  • Purity≥97%
  • MDL No.MFCD00007289

*For research and further manufacturing use only, not for direct human use.

5-Chloro-2-nitrobenzaldehyde|CS-W007862

Structure of 6628-86-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 6628-86-0
  • Cat. No. CS-W007862
  • Purity ≥97%
  • MDL No. MFCD00007289
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄ClNO₃
  • Molecular Weight 185.56
  • Synonym(s) Benzaldehyde, 5-chloro-2-nitro-
  • SMILES O=CC1=CC(Cl)=CC=C1[N+]([O-])=O

Description

5-Chloro-2-nitrobenzaldehyde features a chlorine substituent at the meta position and a nitro group at the ortho position relative to the aldehyde, creating a strongly electron-deficient aromatic ring. This configuration enhances reactivity in nucleophilic addition and condensation reactions. The compound exhibits bench-stable handling characteristics and integrates readily into complex synthetic sequences requiring polarized carbonyl functionality.

Application

5-Chloro-2-nitrobenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted heterocycles via condensation and cyclization reactions. Its electron-deficient aromatic core enhances reactivity in nucleophilic aromatic substitution, while the aldehyde and nitro groups provide orthogonal functional handles for sequential transformations. Bench-stable and readily purified by recrystallization, it facilitates scalable synthesis of complex scaffolds.

Synthesis

  • Route1

    References

    • STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY Patent: WO2008/156656 A2, 2008 ; Location in patent: Page/Page column 44; 180 ;
  • Route2

    References

    • Hu, Jiantao; Cheng, Yongfeng; Yang, Yiqing; Rao, Yu Chemical Communications, 2011 , vol. 47, # 36 p. 10133 - 10135
  • Route3

    References

    • Hoover, Jessica M.; Stahl, Shannon S. Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16901 - 16910

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H290-H315-H317-H318-H335-H400
Precautionary Statements : P234-P261-P261-P273-P280-P280-P302+P352-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.21
  • LogP   2.0607
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Chloro-2-nitrobenzaldehyde sigma5-Chloro-2-nitrobenzaldehyde manufacturer5-Chloro-2-nitrobenzaldehyde price5-Chloro-2-nitrobenzaldehyde structure5-Chloro-2-nitrobenzaldehyde SDSbuy 5-Chloro-2-nitrobenzaldehyde5-Chloro-2-nitrobenzaldehyde supplier5-Chloro-2-nitrobenzaldehyde uses5-Chloro-2-nitrobenzaldehyde molecular weightprice of 5-Chloro-2-nitrobenzaldehyde5-Chloro-2-nitrobenzaldehyde chemical name formula of 5-Chloro-2-nitrobenzaldehyde
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label