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CS-W001157 4
Total: USD 88.00

D-Norvaline

  • CAS No. 2013-12-9

  • Cat. No. CS-0015963
  • Purity≥97%
  • MDL No.MFCD00008097

*For research and further manufacturing use only, not for direct human use.

D-Norvaline|CS-0015963

Structure of 2013-12-9

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General Information

  • CAS No. 2013-12-9
  • Cat. No. CS-0015963
  • Purity ≥97%
  • MDL No. MFCD00008097
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO₂
  • Molecular Weight 117.15
  • Synonym(s) None
  • SMILES OC([C@@H](CCC)N)=O

Description

D-Norvaline is a non-proteinogenic amino acid featuring a hydrophobic side chain that enhances membrane permeability. This configuration enables efficient incorporation into peptidomimetics and bioactive oligomers under standard synthetic conditions. The stable, bench-ready form facilitates use in medicinal chemistry workflows without requiring stringent handling protocols.

Application

D-Norvaline serves as a valuable chiral building block in peptide synthesis and medicinal chemistry, offering defined stereochemistry for the construction of bioactive peptides and peptidomimetics. Its aliphatic side chain provides favorable solubility and metabolic stability, while its bench-stable nature enables straightforward handling and purification. Functions effectively in standard coupling protocols and supports diverse functionalization strategies.

Synthesis

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      161633-98-3
    • ~%
    • In-stock
      D-Norvaline|CS-0015963
      2013-12-9
    • In-stock
      L-Norvaline|CS-D1371
      6600-40-4

    References

    • Journal of the American Chemical Society, , vol. 116, # 18 p. 8126 - 8132
  • Route2
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      206068-37-3
    • ~95%
    • In-stock
      D-Norvaline|CS-0015963
      2013-12-9

    References

    • European Journal of Organic Chemistry, , # 10 p. 2583 - 2591
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    References

    • Journal of Molecular Catalysis B: Enzymatic, , vol. 94, p. 15 - 22

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.1984
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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