Lot numbers can be found on the outside label of a product:
(R)-2-((tert-Butoxycarbonyl)amino)pentanoic acid
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CAS No. 57521-85-4
- Cat. No. CS-W014816
- Purity≥97%
- MDL No.MFCD00155638
*For research and further manufacturing use only, not for direct human use.
Structure of 57521-85-4
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General Information
- CAS No. 57521-85-4
- Cat. No. CS-W014816
- Purity ≥97%
- MDL No. MFCD00155638
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₀H₁₉NO₄
- Molecular Weight 217.26
- Synonym(s) None
- SMILES CCC[C@H](C(O)=O)NC(OC(C)(C)C)=O
Description
(R)-2-((tert-Butoxycarbonyl)amino)pentanoic acid is a stereochemically defined amino acid derivative featuring a protected α-amino group and a carboxylic acid side chain. This bench-stable building block integrates readily into peptide synthesis workflows, enabling efficient access to chiral peptidomimetics and bioactive sequences under standard conditions.
Application
(R)-2-((tert-Butoxycarbonyl)amino)pentanoic acid serves as a valuable chiral building block in peptide synthesis and medicinal chemistry. The Boc-protected amino group offers excellent stability and orthogonal deprotection compatibility, while the carboxylic acid enables straightforward coupling reactions. Its well-defined stereochemistry ensures high fidelity in asymmetric synthesis, facilitating efficient access to bioactive peptides and heterocyclic scaffolds under standard bench conditions.
Synthesis
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References
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US5206235 A1, ;
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Route2
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154079-55-7 - ~80%
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In-stock
57521-85-4
References
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Poch, Marta Tetrahedron Letters, 1993 , vol. 34, # 48 p. 7781 - 7784
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Route3
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In-stock
24424-99-5 - ~%
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In-stock
57521-85-4
References
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Tetrahedron, , vol. 52, # 34 p. 11215 - 11238
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 75.63
- LogP 1.7644
- H_Acceptors 3
- H_Donors 2
- Rotatable_Bonds 4
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Key Words
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