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CS-W001157 4
Total: USD 88.00

NH2-bicyclo[1.1.1]pentane-C-OH hydrochloride

  • CAS No. 1980045-93-9

  • Cat. No. CS-0185379
  • Purity≥97%
  • MDL No.MFCD27996088

*For research and further manufacturing use only, not for direct human use.

NH2-bicyclo[1.1.1]pentane-C-OH hydrochloride|CS-0185379

Structure of 1980045-93-9

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General Information

  • CAS No. 1980045-93-9
  • Cat. No. CS-0185379
  • Purity ≥97%
  • MDL No. MFCD27996088
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO
  • Molecular Weight 149.62
  • Synonym(s) None
  • SMILES OCC12CC(C1)(C2)N.Cl

Description

This bicyclic alcohol features a primary amine and hydroxyl group on a strained pentane scaffold, delivering enhanced rigidity and polarity. The hydrochloride salt improves solubility and stability for use in medicinal chemistry and peptide conjugation workflows.

Application

(3-Amino-1-bicyclo[1.1.1]pentanyl)methanol hydrochloride serves as a versatile, bench-stable building block for medicinal chemistry and process development. Its rigid bicyclic scaffold imparts conformational constraint, while the primary amine and hydroxymethyl groups enable diverse functionalization—facilitating coupling reactions, derivatization, and incorporation into bioactive heterocycles. The hydrochloride salt enhances solubility and handling, supporting scalable synthesis and purification in standard workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.2819
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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