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CS-W001157 4
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3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride

  • CAS No. 1172097-47-0

  • Cat. No. CS-W000162
  • Purity≥95%
  • MDL No.MFCD09971722

*For research and further manufacturing use only, not for direct human use.

3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride|CS-W000162

Structure of 1172097-47-0

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General Information

  • CAS No. 1172097-47-0
  • Cat. No. CS-W000162
  • Purity ≥95%
  • MDL No. MFCD09971722
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀ClNO₂
  • Molecular Weight 163.60
  • Synonym(s) None
  • SMILES Cl.O=C(O)C12CC(N)(C1)C2

Description

3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride delivers a rigid, strain-engineered scaffold with a polar amine and carboxylic acid functionality. This bench-stable derivative features enhanced solubility and predictable conformational behavior, enabling efficient incorporation into bioactive molecules and peptidomimetics under standard conditions.

Application

3-Aminobicyclo[1.1.1]pentane-1-carboxylic acid hydrochloride serves as a rigid, conformationally constrained building block for medicinal chemistry and peptide mimicry. Its bicyclic scaffold imparts high metabolic stability and defined spatial orientation, enabling precise placement of pharmacophoric elements. The amine and carboxylic acid functionalities offer direct handles for derivatization via standard coupling reactions, while the hydrochloride salt ensures excellent solubility and bench stability. This compound facilitates rapid access to diverse heterocyclic scaffolds and is particularly useful in fragment-based drug discovery campaigns requiring compact, three-dimensional architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.3742
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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