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CS-W001157 4
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1-(3-Aminopropyl)-2-pyrrolidinone

  • CAS No. 7663-77-6

  • Cat. No. CS-0071095
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(3-Aminopropyl)-2-pyrrolidinone|CS-0071095

Structure of 7663-77-6

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General Information

  • CAS No. 7663-77-6
  • Cat. No. CS-0071095
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄N₂O
  • Molecular Weight 142.20
  • Synonym(s) 1-(3-Aminopropyl)pyrrolidin-2-one
  • SMILES O=C1N(CCC1)CCCN

Description

N-(3-Aminopropyl)-2-pyrrolidinone (PYR) conjugates (VPA-PYR) of valproic acid (VA) have been investigated for their anticonvulsant activity in mice. It is the -lactam form of isoputreanine.N-(3-Aminopropyl)-2-pyrrolidinone was used in the simultaneous determination of total polyamines and three of their non amino acid metabolites in urine by capillary gas-chromatographic method with nitrogen-phosphorus detection.

Synthesis

  • Route1
    • null|null
      201230-82-2
    • null|null
      34155-45-8
    • ~87%
    • In-stock
      1-(3-Aminopropyl)-2-pyrrolidinone|CS-0071095
      7663-77-6
    • Octahydropyrrolo[1,2-a]pyrimidine|CS-1661437
      57672-23-8

    References

    • Tetrahedron Letters, , vol. 38, # 24 p. 4315 - 4318
  • Route2

    References

    • Amino Acids, , vol. 40, # 1 p. 197 - 204
  • Route3
    • 3-[(prop-2-en-1-yl)amino]propanenitrile|CS-0239842
      34508-81-1
    • ~%
    • In-stock
      1-(3-Aminopropyl)-2-pyrrolidinone|CS-0071095
      7663-77-6

    References

    • Tetrahedron, , vol. 53, # 51 p. 17449 - 17460

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3267
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.33
  • LogP   -0.0424
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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