Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride

  • CAS No. 1886967-25-4

  • Cat. No. CS-0183673
  • Purity≥97%
  • MDL No.MFCD30803728

*For research and further manufacturing use only, not for direct human use.

3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride|CS-0183673

Structure of 1886967-25-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1886967-25-4
  • Cat. No. CS-0183673
  • Purity ≥97%
  • MDL No. MFCD30803728
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉Cl₂N
  • Molecular Weight 154.03
  • Synonym(s) None
  • SMILES Cl.ClC12CC(N)(C1)C2

Description

This bicyclic amine hydrochloride features a rigid, strained [1.1.1]bicyclo[1.1.1]pentane scaffold bearing a chlorine substituent and a protonated amine group. The structure imparts exceptional stability and enhanced lipophilicity, enabling efficient membrane permeation. This compound serves as a valuable building block in medicinal chemistry for bioisosteric replacement of traditional alkyl or aryl groups, particularly in optimizing metabolic stability and solubility profiles within drug candidates.

Application

3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride serves as a rigid, sterically constrained building block for medicinal chemistry and target-oriented synthesis. Its bicyclic scaffold imparts conformational rigidity, while the primary amine functionality enables straightforward derivatization via amidation, alkylation, or reductive amination. The chloride salt enhances solubility and stability, facilitating handling and purification in standard laboratory workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.2808
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1886967-25-4 sigma1886967-25-4 manufacturer1886967-25-4 price1886967-25-4 structure1886967-25-4 SDSbuy 1886967-25-41886967-25-4 supplier1886967-25-4 uses1886967-25-4 molecular weightprice of 1886967-25-41886967-25-4 chemical name formula of 1886967-25-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label