3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride

Name: 3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2197502-05-7
Cat. No. CS-0167520
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride|CS-0167520

Structure of 2197502-05-7

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 2197502-05-7
Cat. No. CS-0167520
Purity ≥98%
MDL No. None
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₂ClNO
Molecular Weight 149.62
Synonym(s) 3-Methoxy-bicyclo[1.1.1]pent-1-ylamine hydrochloride
SMILES NC1(C2)CC2(OC)C1.[H]Cl

Description

3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride features a rigid, strained bicyclic core that imparts exceptional metabolic stability and conformational restraint. The methoxy group enhances solubility and modulates electronic properties, while the protonated amine ensures high water solubility and salt stability. This compound serves as a valuable scaffold in medicinal chemistry for probing steric and electronic effects in bioactive molecule design.

Application

3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride serves as a rigid, conformationally constrained amine building block for medicinal chemistry and synthetic organic applications. Its bicyclic scaffold imparts enhanced metabolic stability and defined spatial orientation, facilitating precise pharmacophore positioning. The methoxy group provides moderate polarity and handles well under standard coupling conditions, while the hydrochloride salt ensures excellent solubility and bench stability. Functions effectively in amide bond formation, reductive amination, and transition-metal-catalyzed cross-couplings, enabling efficient access to complex heterocyclic scaffolds and API intermediates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 35.25
LogP 0.6884
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Bridge Rings compounds Other bridge ring compounds

Building Blocks Skeleton Fatty ring compounds Cyclobutane compounds

Key Words

2197502-05-7 sigma2197502-05-7 manufacturer2197502-05-7 price2197502-05-7 structure2197502-05-7 SDSbuy 2197502-05-72197502-05-7 supplier2197502-05-7 uses2197502-05-7 molecular weightprice of 2197502-05-72197502-05-7 chemical name formula of 2197502-05-7

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride

CAS No. 2197502-05-7

Recommended Products