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CS-W001157 4
Total: USD 88.00

1-(Bromomethyl)bicyclo[1.1.1]pentane

  • CAS No. 161043-38-5

  • Cat. No. CS-0052834
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(Bromomethyl)bicyclo[1.1.1]pentane|CS-0052834

Structure of 161043-38-5

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General Information

  • CAS No. 161043-38-5
  • Cat. No. CS-0052834
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉Br
  • Molecular Weight 161.04
  • Synonym(s) 1-(bromomethyl)bicyclo[1.1.1]pentane5
  • SMILES BrCC12CC(C1)C2

Description

1-(Bromomethyl)bicyclo[1.1.1]pentane features a highly strained, rigid cage structure that imparts exceptional stability and reactivity control. The bromomethyl group enables efficient functionalization in cross-coupling and bioconjugation workflows, while the bicyclic framework resists decomposition under standard conditions. This compound serves as a robust scaffold for probe development and medicinal chemistry applications.

Application

1-(Bromomethyl)bicyclo[1.1.1]pentane serves as a versatile, sterically constrained alkylating agent enabling efficient introduction of the bicyclo[1.1.1]pentane scaffold into diverse molecular architectures. Its primary bromide functionality facilitates nucleophilic substitution under mild conditions, offering high functional group tolerance and excellent bench stability. The rigid, compact structure enhances metabolic stability and modulates physicochemical properties in medicinal chemistry applications, making it a practical building block for targeted synthesis of bioactive compounds and advanced intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2920
Class : 8,3
Packing Group : Ⅱ
Hazard Statements : H225-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.1814
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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