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CS-W001157 4
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(αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-pyridinepropanoic acid

  • CAS No. 185379-40-2

  • Cat. No. CS-0020091
  • Purity≥97%
  • MDL No.MFCD00672564

*For research and further manufacturing use only, not for direct human use.

(αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-pyridinepropanoic acid|CS-0020091

Structure of 185379-40-2

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General Information

  • CAS No. 185379-40-2
  • Cat. No. CS-0020091
  • Purity ≥97%
  • MDL No. MFCD00672564
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₀N₂O₄
  • Molecular Weight 388.42
  • Synonym(s) (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-pyridinepropanoic acid
  • SMILES O=C([C@H](CC1=NC=CC=C1)NC(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O)O

Description

This fluorenylmethoxycarbonyl-protected pyridinealanine derivative features a bench-stable, electron-deficient pyridine ring that facilitates efficient coupling in peptide synthesis. The α-chiral center enables stereoselective incorporation into bioactive sequences, while the Cbz group ensures orthogonal protection during multi-step assembly.

Synthesis

  • Route1
    • null|null
      625096-08-4
    • ~61%
    • In-stock
      (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-pyridinepropanoic acid|CS-0020091
      185379-40-2

    References

    • Tabanella, Stefania; Valancogne, Ingrid; Jackson, Richard F W Organic and biomolecular chemistry, 2003 , vol. 1, # 23 p. 4254 - 4261
  • Route2
    • null|null
      109-04-6
    • ~%
    • In-stock
      (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-pyridinepropanoic acid|CS-0020091
      185379-40-2

    References

    • Organic and biomolecular chemistry, , vol. 1, # 23 p. 4254 - 4261
  • Route3

    References

    • Organic and biomolecular chemistry, , vol. 1, # 23 p. 4254 - 4261

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   88.52
  • LogP   3.616
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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