1-tert-Butyl 2-ethyl (2S)-4-oxopiperidine-1,2-dicarboxylate

Name: 1-tert-Butyl 2-ethyl (2S)-4-oxopiperidine-1,2-dicarboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 180854-44-8
Cat. No. CS-0052402
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-tert-Butyl 2-ethyl (2S)-4-oxopiperidine-1,2-dicarboxylate|CS-0052402

Structure of 180854-44-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 180854-44-8
Cat. No. CS-0052402
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₂₁NO₅
Molecular Weight 271.31
Synonym(s) (S)-1-tert-Butyl 2-ethyl 4-oxopiperidine-1,2-dicarboxylate
SMILES CCOC(=O)[C@@H]1CC(=O)CCN1C(=O)OC(C)(C)C

Description

This chiral piperidine derivative features a bench-stable, moisture-tolerant scaffold with defined stereochemistry at the 2-position. The tert-butyl and ethyl ester groups enable straightforward functionalization, while the 4-oxo moiety provides a reactive handle for downstream transformations in medicinal chemistry applications.

Application

1-tert-Butyl 2-ethyl (2S)-4-oxopiperidine-1,2-dicarboxylate serves as a versatile chiral building block in synthetic organic chemistry, enabling stereoselective synthesis of piperidine-based scaffolds. The protected amine and ester functionalities offer orthogonal reactivity, facilitating downstream transformations such as reductive amination, nucleophilic substitution, and ring functionalization. Bench-stable and readily purified by chromatography, it functions effectively in multi-step sequences for medicinal chemistry and natural product synthesis.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 72.91
LogP 1.5181
H_Acceptors 5
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

180854-44-8 sigma180854-44-8 manufacturer180854-44-8 price180854-44-8 structure180854-44-8 SDSbuy 180854-44-8180854-44-8 supplier180854-44-8 uses180854-44-8 molecular weightprice of 180854-44-8180854-44-8 chemical name formula of 180854-44-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-tert-Butyl 2-ethyl (2S)-4-oxopiperidine-1,2-dicarboxylate

CAS No. 180854-44-8

Recommended Products