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CS-W001157 4
Total: USD 88.00

(S)-(-)-1-Boc-4-oxopiperidine-2-carboxylic acid

  • CAS No. 198646-60-5

  • Cat. No. CS-W001492
  • Molecule weight243.26
  • Purity≥97%
  • MDL No.MFCD03094867

*For research and further manufacturing use only, not for direct human use.

(S)-(-)-1-Boc-4-oxopiperidine-2-carboxylic acid|CS-W001492

Structure of 198646-60-5

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General Information

  • CAS No. 198646-60-5
  • Cat. No. CS-W001492
  • Purity ≥97%
  • MDL No. MFCD03094867
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇NO₅
  • Molecular Weight 243.26
  • Synonym(s) 1-(Tert-butoxycarbonyl)-4-oxopiperidine-2-carboxylic acid
  • SMILES O=C1CCN([C@@H](C1)C(=O)O)C(=O)OC(C)(C)C

Description

(S)-(-)-1-Boc-4-oxopiperidine-2-carboxylic acid is a stereochemically defined, bench-stable building block featuring a protected piperidone core. This configurationally pure intermediate integrates seamlessly into synthetic routes requiring chiral nitrogen heterocycles, offering predictable reactivity in peptide coupling and cascade cyclization processes.

Application

(S)-(-)-1-Boc-4-oxopiperidine-2-carboxylic acid serves as a key chiral building block for the synthesis of bioactive heterocycles and peptide-derived scaffolds. The Boc-protected amine and α-keto functionality enable sequential functionalization, including reductive amination and nucleophilic addition reactions. Its bench-stable nature and compatibility with standard purification protocols facilitate efficient incorporation into complex molecular architectures relevant to medicinal chemistry campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   83.91
  • LogP   1.0396
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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