Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 5-formylthiophene-2-carboxylate

  • CAS No. 67808-64-4

  • Cat. No. CS-W002832
  • Purity≥98%
  • MDL No.MFCD01859942

*For research and further manufacturing use only, not for direct human use.

Methyl 5-formylthiophene-2-carboxylate|CS-W002832

Structure of 67808-64-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 67808-64-4
  • Cat. No. CS-W002832
  • Purity ≥98%
  • MDL No. MFCD01859942
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆O₃S
  • Molecular Weight 170.19
  • Synonym(s) T5SJ BVH EVO1 [WLN]
  • SMILES COC(=O)c1ccc(s1)C=O

Description

Methyl 5-formylthiophene-2-carboxylate features a thiophene core bearing both aldehyde and ester functionalities, enabling direct incorporation into cross-coupling and condensation reactions. The electron-deficient ring facilitates nucleophilic addition, while the formyl group offers versatility in imine formation and conjugation. This bifunctional scaffold supports rapid access to complex heterocyclic architectures under standard conditions.

Application

Methyl 5-formylthiophene-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted thiophenes and fused polycycles. The conjugated aldehyde and ester functionalities support diverse transformations including Wittig reactions, nucleophilic additions, and transition-metal-catalyzed couplings. Its bench-stable nature and compatibility with common protecting group strategies facilitate straightforward purification and integration into multi-step sequences for medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • In-stock
      5-Formylthiophene-2-carboxylic acid|CS-0017900
      4565-31-5
    • null|null
      74-88-4
    • ~87%
    • In-stock
      Methyl 5-formylthiophene-2-carboxylate|CS-W002832
      67808-64-4

    References

    • Goddard Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 1 p. 17 - 28
  • Route2
    • 2-Thiophenecarboxylic acid, 5-(hydroxymethyl)-, methyl ester|CS-0626260
      530145-16-5
    • ~72%
    • In-stock
      Methyl 5-formylthiophene-2-carboxylate|CS-W002832
      67808-64-4

    References

    • CHONG KUN DANG PHARMACEUTICAL CORP. Patent: WO2004/37808 A1, 2004 ; Location in patent: Page 14-15; 93 ;
  • Route3
    • 2-(5-Bromothiophen-2-yl)-1,3-dioxolane|CS-0574842
      52157-62-7
    • null|null
      79-22-1
    • ~%
    • In-stock
      Methyl 5-formylthiophene-2-carboxylate|CS-W002832
      67808-64-4

    References

    • WO2004/13130 A1, ; Page 203 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.37
  • LogP   1.3472
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Methyl 5-formylthiophene-2-carboxylate sigmaMethyl 5-formylthiophene-2-carboxylate manufacturerMethyl 5-formylthiophene-2-carboxylate priceMethyl 5-formylthiophene-2-carboxylate structureMethyl 5-formylthiophene-2-carboxylate SDSbuy Methyl 5-formylthiophene-2-carboxylateMethyl 5-formylthiophene-2-carboxylate supplierMethyl 5-formylthiophene-2-carboxylate usesMethyl 5-formylthiophene-2-carboxylate molecular weightprice of Methyl 5-formylthiophene-2-carboxylateMethyl 5-formylthiophene-2-carboxylate chemical name formula of Methyl 5-formylthiophene-2-carboxylate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label