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Bromoacetamido-PEG3-C2-Boc

  • CAS No. 1807537-33-2

  • Cat. No. CS-0114515
  • Molecule weight398.29
  • Purity≥97%
  • MDL No.MFCD28505521

*For research and further manufacturing use only, not for direct human use.

Bromoacetamido-PEG3-C2-Boc|CS-0114515

Structure of 1807537-33-2

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General Information

  • CAS No. 1807537-33-2
  • Cat. No. CS-0114515
  • Purity ≥97%
  • MDL No. MFCD28505521
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₈BrNO₆
  • Molecular Weight 398.29
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCNC(CBr)=O

Description

Bromoacetamido-PEG3-C2-Boc features a reactive bromoacetamido group flanked by a PEG3 spacer and a C2 linker, terminating in a Boc-protected amine. This bifunctional reagent enables site-specific conjugation under mild conditions, combining efficient coupling with excellent stability during storage and handling.

Application

Bromoacetamido-PEG3-C2-Boc serves as a versatile bifunctional linker for bioconjugation and peptide synthesis, combining a reactive bromoacetamide group with a stable Boc-protected amine. The PEG3 spacer provides solubility and reduced steric hindrance, enabling efficient coupling in aqueous or mixed solvent systems. Its bench-stable Boc group allows for selective deprotection under mild acidic conditions, facilitating sequential functionalization. Widely used in the construction of site-specific conjugates and functionalized intermediates for drug discovery.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   83.09
  • LogP   1.2791
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   13

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