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CS-W001157 4
Total: USD 88.00

Br-PEG3-C2-Boc

  • CAS No. 782475-37-0

  • Cat. No. CS-0108229
  • Purity≥97%
  • MDL No.MFCD22574821

*For research and further manufacturing use only, not for direct human use.

Br-PEG3-C2-Boc|CS-0108229

Structure of 782475-37-0

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General Information

  • CAS No. 782475-37-0
  • Cat. No. CS-0108229
  • Purity ≥97%
  • MDL No. MFCD22574821
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₅BrO₅
  • Molecular Weight 341.24
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCBr

Description

Br-PEG3-C2-Boc features a bromide handle flanked by a triethylene glycol spacer and a tert-butoxycarbonyl-protected amine. This bifunctional intermediate enables site-specific conjugation and orthogonal functionalization in peptide synthesis and bioconjugate chemistry, offering enhanced solubility and stability under standard conditions.

Application

Br-PEG3-C2-Boc serves as a versatile bifunctional building block for the synthesis of PEGylated conjugates and bioactive molecules. The bromide functionality enables efficient coupling via SN2 reactions, while the Boc-protected amine facilitates selective deprotection and further functionalization. Its three-ethylene glycol spacer provides enhanced solubility and stability in aqueous environments, making it ideal for applications in peptide modification, antibody-drug conjugation, and drug delivery systems.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   53.99
  • LogP   2.1629
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   11

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